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Host
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Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 20881-1-AP (same clone as 20881-1-PBS)

    WB analysis using 20881-1-AP (same clone as 20881-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20881-1-AP (SYT10 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20881-1-PBS in a different storage buffer formulation.

Synaptotagmin-10 Polyclonal antibody, PBS Only

Synaptotagmin-10 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 20881-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

SytX, SYT10, Synaptotagmin X

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

20881-1-PBS targets Synaptotagmin-10 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Synaptotagmin-10 fusion protein Ag15018 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 synaptotagmin X
别名 SytX, SYT10, Synaptotagmin X
计算分子量 523 aa, 59 kDa
观测分子量70 kDa
GenBank蛋白编号BC101024
基因名称 Synaptotagmin-10
Gene ID (NCBI) 341359
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ6XYQ8
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (PMID: 8058779). SYT10 (synaptotagmin-10) functions as a Ca2+ sensor to trigger IGF-1 exocytosis in neurons. Loss of Syt10 impairs activity-dependent IGF-1 secretion in olfactory bulb neurons and results in smaller neurons and an overall reduction in the number of synapses (PMID: 21496647).