验证数据展示
产品信息
66437-1-PBS targets Syntaxin 1A / Syntaxin 1B in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat, rabbit, pig samples.
经测试应用 | WB, IHC, IF-P, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat, rabbit, pig |
免疫原 | Syntaxin 1A / Syntaxin 1B fusion protein Ag10257 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | syntaxin 1B |
别名 | STX1B, STX1B1, STX1B2, Syntaxin 1A / Syntaxin 1B, syntaxin 1B, Syntaxin 1B1, Syntaxin 1B2 |
计算分子量 | 288 aa, 33 kDa |
观测分子量 | 33 kDa, 55 kDa |
GenBank蛋白编号 | BC062298 |
基因名称 | STX1B |
Gene ID (NCBI) | 112755 |
RRID | AB_2881807 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P61266 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Syntaxins are a family of transmembrane proteins that belong to the SNARE complex (PMID: 11737951). In conjunction with other SNAREs and with the cytoplasmic NSF and SNAP proteins, syntaxins mediate vesicle fusion in diverse vesicular transport processes along the exocytic and the endocytic pathway (PMID: 11737951). Syntaxin 1A and 1B, two closely related isoforms of syntaxin 1, are involved in synaptic vesicle docking and fusion during neurotransmitter release (PMID: 7690687; 1321498; 18691641). This antibody raised against 1-263 aa of human syntaxin 1B detects a ~33 kDa band of syntaxin 1 and an additional band of 55-60 kDa, which probably represents a syntaxin 1 dimer (PMID: 10100611).