验证数据展示
产品信息
68096-1-PBS targets Syntenin-1 in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | Human |
免疫原 | Syntenin-1 fusion protein Ag18078 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | syndecan binding protein (syntenin) |
别名 | MDA 9, MDA9, Scaffold protein Pbp1, SDCBP, ST1, SYCL, Syndecan binding protein 1, Syntenin 1, TACIP18 |
计算分子量 | 298 aa, 32 kDa |
观测分子量 | 30 kDa |
GenBank蛋白编号 | BC113674 |
基因名称 | Syntenin-1 |
Gene ID (NCBI) | 6386 |
RRID | AB_2918833 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | O00560 |
储存缓冲液 | PBS Only |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Syntenin-1, also known as SDCBP (syndecan binding protein) and MDA-9 (melanoma differentiation-associated protein 9), was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. Syntenin-1 is a PDZ-domain-containing molecule that has many interaction partners, and regulates transmembrane-receptor trafficking, cell adhesion, tumor-cell metastasis and neuronal-synapse function. Syntenin-1 is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.