验证数据展示
产品信息
25697-1-PBS targets TACC3 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IHC, IF/ICC, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | TACC3 fusion protein Ag22516 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | transforming, acidic coiled-coil containing protein 3 |
Synonyms | Tacc4, TACC 3, Maskin, ERIC-1, ERIC1 |
Calculated Molecular Weight | 838 aa, 91 kDa |
Observed Molecular Weight | 130 kDa |
GenBank Accession Number | BC111771 |
Gene Symbol | TACC3 |
Gene ID (NCBI) | 10460 |
RRID | AB_2880199 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9Y6A5 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TACC3, also known as ERIC 1, belongs to the TACC family. TACC family members TACC1, TACC2, and TACC3 map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 8, 10, and 4. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. It plays a role in the microtubule-dependent coupling of the nucleus and the centrosome and involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors.