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TBL1X Polyclonal antibody

TBL1X Polyclonal Antibody for WB, IHC, ELISA
Cat No. 13540-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, ELISA and More (3)

EBI, SMAP55, TBL1, TBL1X

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inmouse pancreas tissue
Positive IHC detected inmouse brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2400
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

13540-1-AP targets TBL1X in WB, IP, IHC, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用WB, IP, CoIP, ChIP
经测试反应性 human, mouse, rat
文献引用反应性human, mouse
免疫原 TBL1X fusion protein Ag4477 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 transducin (beta)-like 1X-linked
别名 EBI, SMAP55, TBL1, TBL1X
计算分子量 526 aa, 57 kDa
观测分子量 57 kDa
GenBank蛋白编号BC032708
基因名称 TBL1X
Gene ID (NCBI) 6907
RRIDAB_2199783
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO60907
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TBL1X is an essential subunit of the nuclear receptor corepressor (NCoR)-silencing mediator for retinoid and thyroid hormone receptors (SMRT) complex, the major TH receptor (TR) corepressor (CoR) involved in T3-regulated gene expression. TBL1X defects were recently associated with central hypothyroidism and hearing loss. (PMID: 30591955, PMID: 27603907)

实验方案

Product Specific Protocols
WB protocol for TBL1X antibody 13540-1-APDownload protocol
IHC protocol for TBL1X antibody 13540-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle

Development

Setd5 is essential for mammalian development and the co-transcriptional regulation of histone acetylation.

Authors - Anna B Osipovich
humanWB,IP

Int J Biol Sci

TBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma.

Authors - Hongjuan Xu
  • KD Validated
mouseWB,CoIP,ChIP

Nat Commun

The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate

Authors - Andreas Lackner
humanWB

Cell Chem Biol

HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation

Authors - Yufeng Xiao
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