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TCF1/TCF7 Recombinant antibody, PBS Only

TCF1/TCF7 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241154D2

Cat no : 84089-4-PBS

Print datasheet

Synonyms

TCF7, TCF-1, TCF1, TCF 7, TCF 1

验证数据展示

  • WB analysis using 84089-4-RR (same clone as 84089-4-PBS)

    WB analysis using 84089-4-RR (same clone as 84089-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84089-4-RR (TCF7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84089-4-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy TCF7 Ready-To-Use IHC Kit. TCF7 primary antibody included.

产品信息

The immunogen of 84089-4-PBS is TCF1/TCF7 Fusion Protein expressed in E. coli.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen TCF1/TCF7 fusion protein Ag5792 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name transcription factor 7 (T-cell specific, HMG-box)
Synonyms TCF7, TCF-1, TCF1, TCF 7, TCF 1
Calculated Molecular Weight 42 kDa
Observed Molecular Weight 58 kDa
GenBank Accession NumberBC048769
Gene Symbol TCF7
Gene ID (NCBI) 6932
ENSEMBL Gene IDENSG00000081059
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP36402
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TCF7, also known as TCF1, belongs to the TCF/LEF family. TCF7 is part of the Wnt signaling pathway and plays an important role in the differentiation and self-renewal of memory T cells. It has been found that TCF7 is necessary to revive T cells in response to PD-1 blockade against viral infection or cancer. TCF7 is mainly expressed in T-cells and is also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium. TCF7 has 16 isoforms with the molecular mass of 28-54 kDa (PMID: 34044317).