• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

TCTN3 Polyclonal antibody, PBS Only

TCTN3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 16085-1-PBS

Print datasheet

Synonyms

TECT3, TCTN 3, PSEC0041, OFD4, JBTS18

验证数据展示

  • IHC staining of human lung using 16085-1-AP (same clone as 16085-1-PBS)

    IHC staining of human lung using 16085-1-AP (same clone as 16085-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung using 16085-1-AP (TCTN3 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 16085-1-PBS in a different storage buffer formulation.

  • WB analysis using 16085-1-AP (same clone as 16085-1-PBS)

    WB analysis using 16085-1-AP (same clone as 16085-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16085-1-AP (TCTN3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16085-1-PBS in a different storage buffer formulation.

产品信息

16085-1-PBS targets TCTN3 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen TCTN3 fusion protein Ag9084 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name tectonic family member 3
Synonyms TECT3, TCTN 3, PSEC0041, OFD4, JBTS18
Calculated Molecular Weight 607 aa, 66 kDa
Observed Molecular Weight 66 kDa
GenBank Accession NumberBC009494
Gene Symbol TCTN3
Gene ID (NCBI) 26123
RRIDAB_10638442
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6NUS6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TCTN3 (tectonic-3 or TECT3) is a type I membrane protein that belongs to the tectonic family, which consists of TCTN1, TCTN2 and TCTN3. Studies in mice suggest that tectonic may be involved in Hedgehog (Hh) signaling, and essential for ciliogenesis. Tectonic is component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. TCTN3 is necessary for transduction of the sonic hedgehog (SHH) signaling pathway. Orofaciodigital syndromes (OFDSs) consist of a group of heterogeneous disorders characterized by abnormalities in the oral cavity, face, and digits and associated phenotypic abnormalities. Recently, TCTN3 mutations are found as the cause of an extreme form of OFD associated with bone dysplasia, tibial defect, cystic kidneys, and brain anomalies.