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THSD7A Polyclonal antibody, PBS Only

THSD7A Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 28524-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 28524-1-AP (same clone as 28524-1-PBS)

    WB analysis using 28524-1-AP (same clone as 28524-1-PBS)

    mouse kidney tissue was subjected to SDS PAGE followed by western blot with 28524-1-AP (THSD7A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28524-1-PBS in a different storage buffer formulation.

产品信息

28524-1-PBS targets THSD7A in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen THSD7A fusion protein Ag29107 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name thrombospondin, type I, domain containing 7A
Synonyms
Calculated Molecular Weight 185 kDa
Observed Molecular Weight240-250 kDa
GenBank Accession NumberNM_015204
Gene Symbol THSD7A
Gene ID (NCBI) 221981
RRIDAB_2918172
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UPZ6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Thrombospondin type-1 domain-containing protein 7A (THSD7A) is a membrane-associated N-glycoprotein with a molecular weight of 250 kDa, which can be cleaved to release a 210-kDa soluble form (PMID: 22194972; 27214550). THSD7A has a role in angiogenesis. It mediates endothelial cell migration and tube formation (PMID: 2002048). THSD7A has been identified as a second autoantigen involved in adult idiopathic membranous nephropathy in addition to PLA2R1 (PMID: 25394321).