TIMP-2 Polyclonal antibody

TIMP-2 Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat and More (1)


IHC,ELISA and More (1)



Cat No : 17353-1-AP

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CSC 21K, Metalloproteinase inhibitor 2, TIMP 2, TIMP2, TIMP-2


Positive IHC detected inhuman kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery


17353-1-AP targets TIMP-2 in IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IHC,ELISA
Cited Applications IF, IHC
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, bovine
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TIMP-2 fusion protein Ag10051
Full Name TIMP metallopeptidase inhibitor 2
Synonyms CSC 21K, Metalloproteinase inhibitor 2, TIMP 2, TIMP2, TIMP-2
Calculated molecular weight 220 aa, 24 kDa
GenBank accession numberBC052605
Gene symbol TIMP2
Gene ID (NCBI) 7077
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.


The TIMPs are natural highly specific endogenous inhibitors of MMPs. Human TIMP family consists of four 21-28 kDa proteins known as TIMP1, TIMP2, TIMP3, and TIMP4 encoded by four paralogous genes.TIMPs are vital to the maintenance of ECM homeostasis primarily through their MMP inhibitory functions. TIMP2, a member of the TIMP family, regulates the proteolytic activity of all MMPs and is involved in cell differentiation, growth, migration, angiogenesis, and apoptosis. Urinary TIMP2 has been recently recognized as an early biomarker to predict Acute kidney injury (AKI) in critically ill patients.


Product Specific Protocols
IHC protocol for TIMP-2 antibody 17353-1-APDownload protocol
Standard Protocols
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