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验证数据展示

  • IHC staining of mouse lung using 26647-1-AP

    IHC staining of mouse lung using 26647-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 26647-1-AP (TIMP2 Antibody) at dilution of 1:200 (under 10x lens).

    Ready-to-use IHC kits available with TIMP2 antibody included
  • IHC staining of mouse lung using 26647-1-AP

    IHC staining of mouse lung using 26647-1-AP

    Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 26647-1-AP (TIMP2 Antibody) at dilution of 1:200 (under 40x lens).

    Ready-to-use IHC kits available with TIMP2 antibody included

TIMP2 Polyclonal antibody

TIMP2 Polyclonal Antibody for IHC, ELISA
Cat No. 26647-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, ELISA

别名

CSC 21K, Metalloproteinase inhibitor 2, TIMP 2, TIMP2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IHC detected inmouse lung tissue, human kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy TIMP2 Ready-To-Use IHC Kit. TIMP2 primary antibody included.

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

26647-1-AP targets TIMP2 in IHC, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human, mouse
免疫原 TIMP2 fusion protein Ag24436 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 TIMP metallopeptidase inhibitor 2
别名 CSC 21K, Metalloproteinase inhibitor 2, TIMP 2, TIMP2
计算分子量 220 aa, 24 kDa
GenBank蛋白编号BC052605
基因名称 TIMP2
Gene ID (NCBI) 7077
RRIDAB_2880587
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP16035
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The TIMPs are natural highly specific endogenous inhibitors of MMPs. Human TIMP family consists of four 21-28 kDa proteins known as TIMP1, TIMP2, TIMP3, and TIMP4 encoded by four paralogous genes.TIMPs are vital to the maintenance of ECM homeostasis primarily through their MMP inhibitory functions. TIMP2, a member of the TIMP family, regulates the proteolytic activity of all MMPs and is involved in cell differentiation, growth, migration, angiogenesis, and apoptosis. Urinary TIMP2 has been recently recognized as an early biomarker to predict Acute kidney injury (AKI) in critically ill patients.

实验方案

Product Specific Protocols
IHC protocol for TIMP2 antibody 26647-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols