验证数据展示
经过测试的应用
| Positive WB detected in | mouse brain tissue, mouse kidney tissue, rat brain tissue, rat kidney tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
15933-1-AP targets TIPRL in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | TIPRL fusion protein Ag8780 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | TIP41, TOR signaling pathway regulator-like (S. cerevisiae) |
| 别名 | TIP, TIP41, TIP41 like protein, TIPRL, Type 2A interacting protein |
| 计算分子量 | 178 aa, 20 kDa |
| 观测分子量 | 33 kDa |
| GenBank蛋白编号 | BC009506 |
| 基因名称 | TIPRL |
| Gene ID (NCBI) | 261726 |
| RRID | AB_3669227 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O75663 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TIPRL, also known as TIP, TIP4, is an inhibitory regulator of protein phosphatase-2A (PP2A) , PP4, and PP6(PMID: 17384681). TIPRL, an evolutionarily conserved protein, plays a critical role in mediating γ-H2AX signal transduction upon DNA damage(PMID: 26717153).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for TIPRL antibody 15933-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |