Anti-Human TLR3/CD283 Rabbit Recombinant Antibody
TLR3/CD283 Recombinant Antibody for FC
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
FC
Conjugate
Unconjugated
CloneNo.
230445G9
验证数据展示
经过测试的应用
| Positive FC detected in | human monocyte-derived immature dendritic cells |
推荐稀释比
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
The immunogen of 98016-2-RR is TLR3/CD283 Fusion Protein expressed in E. coli.
| Tested Applications | FC Application Description |
| Tested Reactivity | Human |
| Immunogen | TLR3/CD283 fusion protein Ag34044 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | toll-like receptor 3 |
| Synonyms | CD283, TLR3, toll like receptor 3 |
| Calculated Molecular Weight | 904 aa, 104 kDa |
| GenBank Accession Number | BC094737 |
| Gene Symbol | TLR3 |
| Gene ID (NCBI) | 7098 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | O15455 |
| Storage Buffer | PBS with 0.09% sodium azide. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
TLR3 belongs to the Toll-like receptor family which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA. Upon recognition of dsRNA, TLR3 transmits signals via the adaptor protein TICAM-1/TRIF, leading to the induction of type I IFN, cytokine/chemokine production, and dendritic cell (DC) maturation (PMID: 18262679).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for TLR3/CD283 antibody 98016-2-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
