Anti-Human TLR3/CD283 Rabbit Recombinant Antibody, PBS Only

TLR3/CD283 Recombinant Antibody for FC (Intra)
Cat No. 98016-2-PBS

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CloneNo. 230445G9

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC (Intra)

TLR3, Toll-like receptor 3, toll like receptor 3, CD283, 230445G9

Formulation:  PBS Only
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -


产品信息

98016-2-PBS targets TLR3/CD283 in FC (Intra) applications and shows reactivity with human samples.

Tested Applications FC (Intra) Application Description
Tested Reactivity human
Immunogen TLR3/CD283 fusion protein Ag34044 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name toll-like receptor 3
Synonyms TLR3, Toll-like receptor 3, toll like receptor 3, CD283, 230445G9
Calculated Molecular Weight 904 aa, 104 kDa
GenBank Accession NumberBC094737
Gene Symbol TLR3
Gene ID (NCBI) 7098
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO15455
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TLR3 belongs to the Toll-like receptor family which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA. Upon recognition of dsRNA, TLR3 transmits signals via the adaptor protein TICAM-1/TRIF, leading to the induction of type I IFN, cytokine/chemokine production, and dendritic cell (DC) maturation (PMID: 18262679).

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