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TMBIM6 antagonist-1

TMBIM6 antagonist-1 (BAX-inhibitor-1) 是有潜力的TMBIM6拮抗剂，能够抑制 TMBIM6 与 mTORC2 结合，抑制 mTORC2 活性，调节TMBIM6 释放 Ca2+。

CAS号

123134-61-2

分子式

C15H12N2O3

主要靶点

mTOR

仅限科研使用

Cat No : CM06677

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Synonyms

1-（2-氨基苯基）-3-（3-硝基苯基）-2-丙烯-1-酮|BAX-inhibitor-1|BIA

验证数据展示

  • CAS No.: 123134-61-2

    TMBIM6 antagonist-1
    CAS#: 123134-61-2

产品信息

BIA is a bax inhibitor

CAS号 123134-61-2
分子式 C15H12N2O3
主要靶点 mTOR
主要通路 PI3K/Akt/mTOR信号通路
分子量 268.27
纯度 99.34%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 1-（2-氨基苯基）-3-（3-硝基苯基）-2-丙烯-1-酮|BAX-inhibitor-1|BIA

溶解度

DMSO:11 mg/mL (41 mM)

参考文献

1.Kim H K , Bhattarai K R , Junjappa R P , et al. TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation[J]. Nature Communications, 2020, 11(1).

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2