验证数据展示
经过测试的应用
| Positive WB detected in | human placenta tissue, mouse placenta tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| KD/KO | See 1 publications below |
| WB | See 3 publications below |
产品信息
16564-1-AP targets TMEM11 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human |
| 免疫原 | TMEM11 fusion protein Ag9839 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | transmembrane protein 11 |
| 别名 | C17orf35, PM1, PMI, Protein PM1, TMEM11, transmembrane protein 11 |
| 计算分子量 | 192 aa, 22 kDa |
| 观测分子量 | 22 kDa |
| GenBank蛋白编号 | BC020815 |
| 基因名称 | TMEM11 |
| Gene ID (NCBI) | 8834 |
| RRID | AB_2287468 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P17152 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TMEM11, also named as C17orf35 and PM1, belongs to the TMEM11 family. TMEM11 is a mitochondrial inner-membrane protein facing the matrix. It regulates mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways.(PMID:21274005)
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for TMEM11 antibody 16564-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Elife QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology. | ||
EMBO Rep Inner-membrane proteins PMI/TMEM11 regulate mitochondrial morphogenesis independently of the DRP1/MFN fission/fusion pathways.
| ||
J Cell Biol The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy |
