TMEM165 Recombinant antibody
TMEM165 Recombinant Antibody for IF/ICC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
IF/ICC, ELISA
Conjugate
Unconjugated
CloneNo.
230517B1
验证数据展示
经过测试的应用
Positive IF detected in | HepG2 cells |
推荐稀释比
Application | Dilution |
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Immunofluorescence (IF) | IF : 1:200-1:800 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
83146-1-RR targets TMEM165 in IF, ELISA applications and shows reactivity with Human samples.
Tested Applications | IF/ICC, ELISA Application Description |
Tested Reactivity | Human |
Immunogen | TMEM165 fusion protein Ag14362 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | transmembrane protein 165 |
Synonyms | TMEM165, TMPT27, TPARL, transmembrane protein 165, Transmembrane protein PT27, Transmembrane protein TPARL |
Calculated Molecular Weight | 324 aa, 35 kDa |
GenBank Accession Number | BC003545 |
Gene Symbol | TMEM165 |
Gene ID (NCBI) | 55858 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q9HC07 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Thiopurine methyltransferase or thiopurine S-methyltransferase (TPMT), a member of methyltransferase superfamily, is an enzyme involved in the normal metabolic inactivation of thiopurine drugs such as azathioprine, 6-mercaptopurine and 6-thioguanine. These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation. Defects in the TPMT gene leads to decreased methylation and decreased inactivation of 6MP leading to enhanced bone marrow toxicity which may cause myelosuppression, anemia, bleeding tendency, leukopenia and infection.
实验方案
Product Specific Protocols | |
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IF protocol for TMEM165 antibody 83146-1-RR | Download protocol |
FC protocol for TMEM165 antibody 83146-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |