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  • Featured Product
  • KD/KO Validated

TMEM70 Monoclonal antibody, PBS Only

TMEM70 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C11C3

Cat no : 60195-1-PBS

Print datasheet

Synonyms

TMEM70, transmembrane protein 70

验证数据展示

  • WB analysis of A2780 using 60195-1-Ig (same clone as 60195-1-PBS)

    WB analysis of A2780 using 60195-1-Ig (same clone as 60195-1-PBS)

    A2780 cells were subjected to SDS PAGE followed by western blot with 60195-1-Ig (TMEM70 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

    IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver using 60195-1-Ig(TMEM70 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

    IHC staining of human liver using 60195-1-Ig (same clone as 60195-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver using 60195-1-Ig(TMEM70 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 60195-1-Ig (same clone as 60195-1-PBS)

    WB analysis of HeLa using 60195-1-Ig (same clone as 60195-1-PBS)

    WB result of TMEM70 antibody (60195-1-Ig; 1:1500; incubated at room temperature for 1.5 hours) with sh-Control and sh-TMEM70 transfected HeLa cells. This data was developed using the same antibody clone with 60195-1-PBS in a different storage buffer formulation.

产品信息

60195-1-PBS targets TMEM70 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen TMEM70 fusion protein Ag16947 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name transmembrane protein 70
Synonyms TMEM70, transmembrane protein 70
Calculated Molecular Weight 260 aa, 29 kDa
Observed Molecular Weight 18 kDa
GenBank Accession NumberBC002748
Gene Symbol TMEM70
Gene ID (NCBI) 54968
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ9BUB7
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TMEM70 belongs to the TMEM70 family. It is involved in biogenesis of mitochondrial ATP synthase. Defects in TMEM70 are a cause of mitochondrial encephalocardiomyopathy neonatal due to ATP synthase deficiency (MT-ATPSD). A publication (PMID:21147908) identified TMEM70 gene defect as a pan-ethnic disorder and further redefined it as the most common cause of nuclear-origin ATP synthase deficiency.