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验证数据展示

  • WB analysis of human peripheral blood leukocyte using 24622-1-AP

    WB analysis of human peripheral blood leukocyte using 24622-1-AP

    human peripheral blood leukocytes were subjected to SDS PAGE followed by western blot with 24622-1-AP (DcR1/TNFRSF10C antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

DcR1/TNFRSF10C Polyclonal antibody

DcR1/TNFRSF10C Polyclonal Antibody for WB, ELISA
Cat No. 24622-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

CD263, DCR1, Decoy receptor 1, LIT, Lymphocyte inhibitor of TRAIL, TNFRSF10C, TRAIL R3, TRAIL receptor 3, TRAILR3, TRID

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated

规格: 
50 μL
100 μL
150 μL

¥2200/ 100 μL

浓度: 650 μg/ml

库存：现货

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经过测试的应用

Positive WB detected inhuman peripheral blood leukocyte

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24622-1-AP targets DcR1/TNFRSF10C in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 DcR1/TNFRSF10C fusion protein Ag18399 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
别名 CD263, DCR1, Decoy receptor 1, LIT, Lymphocyte inhibitor of TRAIL, TNFRSF10C, TRAIL R3, TRAIL receptor 3, TRAILR3, TRID
计算分子量 259 aa, 27 kDa
观测分子量60 kDa
GenBank蛋白编号BC125041
基因名称 DcR1
Gene ID (NCBI) 8794
RRIDAB_3085741
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO14798
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Decoy receptor 1 (DcR1), also known as TNFRSF10C, CD263, TRAIL-R3, or TRID, is a member of the TNF-receptor superfamily. DcR1 is a receptor for the cytotoxic ligand TRAIL. In contrast to DR4/TRAIL-R1 and DR5/TRAIL-R2, DcR1 is a glycosylphosphatidylinositol (GPI)-linked membrane molecule that lacks a cytoplasmic region, including the death domain (PMID: 9314565; 9242611). DcR1 is not capable of inducing apoptosis and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis (PMID: 9242610). The apparent molecular weight of DcR1 is larger than the calculated molecular weight of 27 kDa, suggesting the presence of extensive post-translational modifications and/or unusual structural motifs (PMID: 9373179).

实验方案

Product Specific Protocols
WB protocol for DcR1/TNFRSF10C antibody 24622-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols