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TNFRSF13B/CD267 Polyclonal antibody

TNFRSF13B/CD267 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 21520-1-AP

Print datasheet

Synonyms

CD267, TNFRSF13B, TACI, CVID

验证数据展示

  • WB analysis using 21520-1-AP

    WB analysis using 21520-1-AP

    IM-9 cells were subjected to SDS PAGE followed by western blot with 21520-1-AP (TNFRSF13B/CD267 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inIM-9 cells, K-562 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:3000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

21520-1-AP targets TNFRSF13B/CD267 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen TNFRSF13B/CD267 fusion protein Ag16097 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name tumor necrosis factor receptor superfamily, member 13B
Synonyms CD267, TNFRSF13B, TACI, CVID
Calculated Molecular Weight 293 aa, 32 kDa
Observed Molecular Weight 30 kDa
GenBank Accession NumberBC109392
Gene Symbol TNFRSF13B/CD267
Gene ID (NCBI) 23495
RRIDAB_10888631
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO14836
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

实验方案

Product Specific Protocols
WB protocol for TNFRSF13B/CD267 antibody 21520-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols