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CD268/BAFF-R Polyclonal antibody

CD268/BAFF-R Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 22582-1-AP

Print datasheet

Synonyms

TNFRSF13C, BLyS receptor 3, B-cell-activating factor receptor, BAFF-R, BAFFR

验证数据展示

  • IHC staining of human tonsillitis using 22582-1-AP

    IHC staining of human tonsillitis using 22582-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22582-1-AP (TNFRSF13C Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

    Ready-to-use IHC kits available with TNFRSF13C antibody included
  • IHC staining of human tonsillitis using 22582-1-AP

    IHC staining of human tonsillitis using 22582-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22582-1-AP (TNFRSF13C Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

    Ready-to-use IHC kits available with TNFRSF13C antibody included

经过测试的应用

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy TNFRSF13C Ready-To-Use IHC Kit. TNFRSF13C primary antibody included.

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

22582-1-AP targets CD268/BAFF-R in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen CD268/BAFF-R fusion protein Ag18202 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name tumor necrosis factor receptor superfamily, member 13C
Synonyms TNFRSF13C, BLyS receptor 3, B-cell-activating factor receptor, BAFF-R, BAFFR
Calculated Molecular Weight 184 aa, 19 kDa
GenBank Accession NumberBC105123
Gene Symbol TNFRSF13C
Gene ID (NCBI) 115650
RRIDAB_2879126
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
UNIPROT IDQ96RJ3
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).

实验方案

Product Specific Protocols
IHC protocol for CD268/BAFF-R antibody 22582-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols