• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IHC staining of human tonsillitis using 22582-1-AP

    IHC staining of human tonsillitis using 22582-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22582-1-AP (TNFRSF13C Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

    Ready-to-use IHC kits available with TNFRSF13C antibody included
  • IHC staining of human tonsillitis using 22582-1-AP

    IHC staining of human tonsillitis using 22582-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 22582-1-AP (TNFRSF13C Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

    Ready-to-use IHC kits available with TNFRSF13C antibody included

CD268/BAFF-R Polyclonal antibody

CD268/BAFF-R Polyclonal Antibody for IHC, ELISA
Cat No. 22582-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, ELISA

别名

TNFRSF13C, BLyS receptor 3, B-cell-activating factor receptor, BAFF-R, BAFFR

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

经过测试的应用

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy TNFRSF13C Ready-To-Use IHC Kit. TNFRSF13C primary antibody included.

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

22582-1-AP targets CD268/BAFF-R in IHC, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human
免疫原 CD268/BAFF-R fusion protein Ag18202 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 13C
别名 TNFRSF13C, BLyS receptor 3, B-cell-activating factor receptor, BAFF-R, BAFFR
计算分子量 184 aa, 19 kDa
GenBank蛋白编号BC105123
基因名称 TNFRSF13C
Gene ID (NCBI) 115650
RRIDAB_2879126
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen Affinity purified
UNIPROT IDQ96RJ3
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).

实验方案

Product Specific Protocols
IHC protocol for CD268/BAFF-R antibody 22582-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols