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验证数据展示

  • Cytometric bead array standard curve of MP51091-1

    Cytometric bead array standard curve of MP51091-1

    Cytometric bead array standard curve of MP51091-1, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-1-PBS. Detection antibody: 60763-2-PBS. Standard:Ag18512. Range: 0.098-100 ng/mL.

  • Cytometric bead array standard curve of MP51091-2

    Cytometric bead array standard curve of MP51091-2

    Cytometric bead array standard curve of MP51091-2, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-1-PBS. Detection antibody: 60763-3-PBS. Standard:Ag18512. Range: 0.098-100 ng/mL.

CD268/BAFF-R Monoclonal antibody, PBS Only (Capture)

CD268/BAFF-R Monoclonal Antibody for Cytometric bead array, Indirect ELISA
Cat No. 60763-1-PBS

产品说明书

CloneNo. 1D6F7

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

Cytometric bead array, Indirect ELISA

别名

TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TNFRSF13C Ready-To-Use IHC Kit. TNFRSF13C primary antibody included.

产品信息

60763-1-PBS targets CD268/BAFF-R as part of a matched antibody pair:

MP51091-1: 60763-1-PBS capture and 60763-2-PBS detection (validated in Cytometric bead array)

MP51091-2: 60763-1-PBS capture and 60763-3-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 CD268/BAFF-R fusion protein Ag18512 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 13C
别名 TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor
计算分子量 184 aa, 19 kDa
GenBank蛋白编号BC105123
基因名称 TNFRSF13C
Gene ID (NCBI) 115650
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G Magarose purification
UNIPROT IDQ96RJ3
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).