• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • Cytometric bead array standard curve of MP51091-2

    Cytometric bead array standard curve of MP51091-2

    Cytometric bead array standard curve of MP51091-2, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-1-PBS. Detection antibody: 60763-3-PBS. Standard:Ag18512. Range: 0.098-100 ng/mL.

  • Cytometric bead array standard curve of MP51091-4

    Cytometric bead array standard curve of MP51091-4

    Cytometric bead array standard curve of MP51091-4, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-2-PBS. Detection antibody: 60763-3-PBS. Standard:Ag18512. Range: 0.781-100 ng/mL.

CD268/BAFF-R Monoclonal antibody, PBS Only (Detector)

CD268/BAFF-R Monoclonal Antibody for Cytometric bead array, Indirect ELISA
Cat No. 60763-3-PBS

Print datasheet

CloneNo. 2D9D11

Host / Isotype

Mouse / IgM

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Synonyms

TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor

Formulation:  PBS Only
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy TNFRSF13C Ready-To-Use IHC Kit. TNFRSF13C primary antibody included.

产品信息

60763-3-PBS targets CD268/BAFF-R as part of a matched antibody pair:

MP51091-2: 60763-1-PBS capture and 60763-3-PBS detection (validated in Cytometric bead array)

MP51091-4: 60763-2-PBS capture and 60763-3-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen CD268/BAFF-R fusion protein Ag18512 种属同源性预测
Host / Isotype Mouse / IgM
Class Monoclonal
Type Antibody
Full Name tumor necrosis factor receptor superfamily, member 13C
Synonyms TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor
Calculated Molecular Weight 184 aa, 19 kDa
GenBank Accession NumberBC105123
Gene Symbol TNFRSF13C
Gene ID (NCBI) 115650
Conjugate Unconjugated
Form Liquid
Purification MethodCaprylic acid/ammonium sulfate precipitation
UNIPROT IDQ96RJ3
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).