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TNFRSF9/CD137 Monoclonal antibody, PBS Only (Capture)

TNFRSF9/CD137 Monoclonal Antibody for Cytometric bead array, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

Cytometric bead array, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A3B2

Cat no : 68754-1-PBS

Print datasheet

Synonyms

TNFRSF9, ILA, CD137, 4-1BB ligand receptor, 4 1BB ligand receptor

验证数据展示

  • Cytometric bead array standard curve of MP50110-1

    Cytometric bead array standard curve of MP50110-1

    Cytometric bead array standard curve of MP50110-1, TNFRSF9/CD137 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68754-1-PBS. Detection antibody: 68754-2-PBS. Standard:Eg0016. Range:1.563-100 ng/mL.

产品信息

68754-1-PBS targets TNFRSF9/CD137 as part of a matched antibody pair:

MP50110-1: 68754-1-PBS capture and 68754-2-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications Cytometric bead array, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name tumor necrosis factor receptor superfamily, member 9
Synonyms TNFRSF9, ILA, CD137, 4-1BB ligand receptor, 4 1BB ligand receptor
Calculated Molecular Weight 28 kDa
GenBank Accession NumberBC006196
Gene Symbol TNFRSF9/CD137
Gene ID (NCBI) 3604
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ07011
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD137, also known as TNFRSF9 or 4-1BB, is an inducible T cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. CD137 is a transmembrane protein expressed on the surface of activated T-cells. In addition, activation-dependent expression of CD137 has also been found in B lymphocytes, monocytes, and diverse nonlymphoid cell types. CD137 provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity. (PMID: 9826581; 23696891)