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TOR1B Polyclonal antibody, PBS Only

TOR1B Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 21945-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 21945-1-AP (same clone as 21945-1-PBS)

    WB analysis using 21945-1-AP (same clone as 21945-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21945-1-AP (TOR1B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21945-1-PBS in a different storage buffer formulation.

产品信息

21945-1-PBS targets TOR1B in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen TOR1B fusion protein Ag16641 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name torsin family 1, member B (torsin B)
Synonyms
Calculated Molecular Weight 336 aa, 38 kDa
Observed Molecular Weight 34 kDa
GenBank Accession NumberBC015578
Gene Symbol TOR1B
Gene ID (NCBI) 27348
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO14657
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Torsin A is 1 of 4 predicted mammalian torsin ATPases associated with assorted cellular activities (AAA+) proteins (PMID: 20015956). TOR1B (torsin family 1 member B), also called TorsinB (TorB), is similar to TorsinA at the sequence level. TorsinA and TorsinB are both ubiquitously expressed in all cell types though TorsinA is more highly expressed in neurons. TorsinA and TorsinB may be somewhat functionally redundant, with TorsinA being more important in neuronal cells and TorsinB being more important in other tissues (PMID: 24275647). TOR1B serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins,and plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity (PMID: 24275647; 23569223).