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验证数据展示

  • WB analysis using 84267-3-RR (same clone as 84267-3-PBS)

    WB analysis using 84267-3-RR (same clone as 84267-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84267-3-RR (TOR1B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84267-3-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP01175-1

    Cytometric bead array standard curve of MP01175-1

    Cytometric bead array standard curve of MP01175-1, TOR1B Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84267-1-PBS. Detection antibody: 84267-3-PBS. Standard: Ag16641. Range: 0.313-40 ng/mL.

  • Cytometric bead array standard curve of MP01175-2

    Cytometric bead array standard curve of MP01175-2

    Cytometric bead array standard curve of MP01175-2, TOR1B Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84267-2-PBS. Detection antibody: 84267-3-PBS. Standard: Ag16641. Range: 0.313-40 ng/mL.

  • Affinity and Kinetic Characterization of 84267-3-RR

    Affinity and Kinetic Characterization of 84267-3-RR

    Biolayer interferometry (BLl) kinetic assays of 84267-3-RR against Human TOR1B were performed. The affinity constant is 14.5 nM.

TOR1B Recombinant antibody, PBS Only (Detector)

TOR1B Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 84267-3-PBS

产品说明书

CloneNo. 241574A7

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Cytometric bead array, Indirect ELISA

别名

Torsin family 1 member B, Torsin 1B, DQ1, 241574A7

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

84267-3-PBS targets TOR1B as part of a matched antibody pair:

MP01175-1: 84267-1-PBS capture and 84267-3-PBS detection (validated in Cytometric bead array)

MP01175-2: 84267-2-PBS capture and 84267-3-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 TOR1B fusion protein Ag16641 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 torsin family 1, member B (torsin B)
别名 Torsin family 1 member B, Torsin 1B, DQ1, 241574A7
计算分子量 336 aa, 38 kDa
观测分子量 35 kDa
GenBank蛋白编号BC015578
基因名称 TOR1B
Gene ID (NCBI) 27348
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO14657
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Torsin A is 1 of 4 predicted mammalian torsin ATPases associated with assorted cellular activities (AAA+) proteins (PMID: 20015956). TOR1B (torsin family 1 member B), also called TorsinB (TorB), is similar to TorsinA at the sequence level. TorsinA and TorsinB are both ubiquitously expressed in all cell types though TorsinA is more highly expressed in neurons. TorsinA and TorsinB may be somewhat functionally redundant, with TorsinA being more important in neuronal cells and TorsinB being more important in other tissues (PMID: 24275647). TOR1B serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins,and plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity (PMID: 24275647; 23569223).