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  • Featured Product
  • KD/KO Validated

TRBP Monoclonal antibody, PBS Only

TRBP Monoclonal Antibody for WB,Indirect ELISA,IHC

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB,Indirect ELISA,IHC

Conjugate

Unconjugated

CloneNo.

1C9A10

Cat No : 66792-1-PBS

Print datasheet

Synonyms

LOQS, TAR RNA binding protein 2, TARBP2, TRBP, TRBP1, TRBP2

验证数据展示

  • WB analysis using 66792-1-Ig (same clone as 66792-1-PBS)

    WB analysis using 66792-1-Ig (same clone as 66792-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66792-1-Ig (TRBP antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66792-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66792-1-Ig (TRBP antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66792-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66792-1-Ig (TRBP antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66792-1-PBS in a different storage buffer formulation.

产品信息

66792-1-PBS targets TRBP in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB,Indirect ELISA,IHC Application Description
Tested Reactivity Human
Immunogen TRBP fusion protein Ag8269 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name TAR (HIV-1) RNA binding protein 2
Synonyms LOQS, TAR RNA binding protein 2, TARBP2, TRBP, TRBP1, TRBP2
Calculated Molecular Weight 39 kDa
Observed Molecular Weight 43-46 kDa
GenBank Accession NumberBC005860
Gene Symbol TARBP2
Gene ID (NCBI) 6895
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ15633
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC). Within the complex, TARBP2 and DICER1 are required to process precursor miRNAs (pre-miRNA) to mature miRNA and then load them onto EIF2C2/AGO2. It may has a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Otherwise, it binds to the HIV-1 TAR RNA that is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. The endogenous TRBP that was present in HEK293 cells, with apparent molecular masses of 43-46 kDa, are expressed in human cells. (PMID: 16142218)