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TRBP Monoclonal antibody, PBS Only

TRBP Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1C9A10

Cat no : 66792-1-PBS

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Synonyms

LOQS, TAR RNA binding protein 2, TARBP2, TRBP, TRBP1, TRBP2



产品信息

66792-1-PBS targets TRBP in WB, IHC, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen TRBP fusion protein Ag8269 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name TAR (HIV-1) RNA binding protein 2
Synonyms LOQS, TAR RNA binding protein 2, TARBP2, TRBP, TRBP1, TRBP2
Calculated Molecular Weight 39 kDa
Observed Molecular Weight 43-46 kDa
GenBank Accession NumberBC005860
Gene Symbol TRBP
Gene ID (NCBI) 6895
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ15633
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC). Within the complex, TARBP2 and DICER1 are required to process precursor miRNAs (pre-miRNA) to mature miRNA and then load them onto EIF2C2/AGO2. It may has a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Otherwise, it binds to the HIV-1 TAR RNA that is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. The endogenous TRBP that was present in HEK293 cells, with apparent molecular masses of 43-46 kDa, are expressed in human cells. (PMID: 16142218)