TREK1/KCNK2 Polyclonal antibody

TREK1/KCNK2 Polyclonal Antibody for WB, ELISA
Cat No. 26807-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

hTREK 1c, hTREK 1e, K2p2.1, KCNK2, TPKC1, TREK, TREK 1, TREK 1 K(+) channel subunit, TREK1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inLNCaP cells, SH-SY5Y cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

26807-1-AP targets TREK1/KCNK2 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 TREK1/KCNK2 fusion protein Ag25209 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 potassium channel, subfamily K, member 2
别名 hTREK 1c, hTREK 1e, K2p2.1, KCNK2, TPKC1, TREK, TREK 1, TREK 1 K(+) channel subunit, TREK1
计算分子量 411 aa, 46 kDa
观测分子量40-50 kDa
GenBank蛋白编号BC101693
基因名称 TREK1
Gene ID (NCBI) 3776
RRIDAB_3085905
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDO95069
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

The tandem of pore domains in a weak inward rectifying K+ channel (TWIK1, K2P1.1, or KCNK1) and TWIK-related K+channel 1 (TREK1, K2P 2.1, or KCNK2) are members of the two pore domain potassium (K2P) channel family, consisting of 15 channels that regulate the stabilization of resting membrane potential and cellular excitability by wielding background K+ leakage currents (PMID:12580339). TREK1/KCNK2 is sensitive to a wide range of physical and chemical cues. Its main role is to maintain the resting potential of the cell and whilst highly expressed in the nervous system, TREK1/KCNK2 is also expressed in the kidney, heart, lung and smooth muscle cells (PMID:31031627).

实验方案

Product Specific Protocols
WB protocol for TREK1/KCNK2 antibody 26807-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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