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TRIM2 Monoclonal antibody, PBS Only

TRIM2 Monoclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse, Rat, Pig

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1H9C2

Cat no : 67342-1-PBS

Print datasheet

Synonyms

KIAA0517, RING finger protein 86, RNF86, TRIM2, tripartite motif containing 2

验证数据展示

  • IF Staining of mouse brain using 67342-1-Ig (same clone as 67342-1-PBS)

    IF Staining of mouse brain using 67342-1-Ig (same clone as 67342-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using TRIM2 antibody (67342-1-Ig, Clone: 1H9C2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67342-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 67342-1-Ig (same clone as 67342-1-PBS)

    IF Staining of mouse brain using 67342-1-Ig (same clone as 67342-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using TRIM2 antibody (67342-1-Ig, Clone: 1H9C2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67342-1-PBS in a different storage buffer formulation.

  • WB analysis of rat brain using 67342-1-Ig (same clone as 67342-1-PBS)

    WB analysis of rat brain using 67342-1-Ig (same clone as 67342-1-PBS)

    rat brain tissue were subjected to SDS PAGE followed by western blot with 67342-1-Ig (TRIM2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67342-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 67342-1-Ig (same clone as 67342-1-PBS)

    IHC staining of mouse brain using 67342-1-Ig (same clone as 67342-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 67342-1-Ig (TRIM2 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67342-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 67342-1-Ig (same clone as 67342-1-PBS)

    IHC staining of mouse brain using 67342-1-Ig (same clone as 67342-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 67342-1-Ig (TRIM2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67342-1-PBS in a different storage buffer formulation.

产品信息

67342-1-PBS targets TRIM2 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with Human, Mouse, Rat, Pig samples.

Tested Applications WB, IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity Human, Mouse, Rat, Pig
Immunogen TRIM2 fusion protein Ag14637 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name tripartite motif-containing 2
Synonyms KIAA0517, RING finger protein 86, RNF86, TRIM2, tripartite motif containing 2
Calculated Molecular Weight 744 aa, 82 kDa
Observed Molecular Weight 70-85 kDa
GenBank Accession NumberBC011052
Gene Symbol TRIM2
Gene ID (NCBI) 23321
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ9C040
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Tripartite motif-containing 2(TRIM2) is an E3 ubiquitin ligase which directs proteasome-mediated degradation of target proteins by the ubiquitination of NEFL and phosphorylation of BCL2L11. This protein contains an N-terminal RING domain, followed by a B-box-2 domain, a coiled-coil region, and 6 C-terminal NHL repeats. TRIM2 involves in the apoptotic response to ischemia via directing degradation of BIM protein, thus has a role in neuroprotection.