验证数据展示
经过测试的应用
| Positive WB detected in | HT-1080 cells, mouse testis tissue, Jurkat cells |
| Positive IP detected in | mouse testis tissue |
It works great for western. By Dr. Soory
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
19602-1-AP targets TRIP13 in WB, IHC, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, IP, ELISA Application Description |
| 文献引用应用 | WB, IHC, IF, IP, CoIP |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, mouse |
| 免疫原 | TRIP13 fusion protein Ag6595 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | thyroid hormone receptor interactor 13 |
| 别名 | 16E1 BP, 16E1BP, PCH2, TR interacting protein 13, TRIP 13, TRIP13 |
| 计算分子量 | 49 kDa |
| 观测分子量 | 49 kDa |
| GenBank蛋白编号 | BC000404 |
| 基因名称 | TRIP13 |
| Gene ID (NCBI) | 9319 |
| RRID | AB_10642702 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q15645 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TRIP13 gene encodes thyroid receptor-interacting protein 13, that interact with thyroid hormone receptors, also known as human papillomavirus type 16 E1 protein-binding protein (16E1BP). This protein belongs to the AAA ATPase family and the PCH2 subfamily. TRIP13 gene may be one of the several playing roles in early-stage non-small cell lung cancer. TRIP13 also functions in chromosome recombination and chromosome structure development during meiosis, and it is required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for TRIP13 antibody 19602-1-AP | Download protocol |
| IP protocol for TRIP13 antibody 19602-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Adv Res Tetrahydrocurcumin targets TRIP13 inhibiting the interaction of TRIP13/USP7/c-FLIP to mediate c-FLIP ubiquitination in triple-negative breast cancer | ||
Nat Commun TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer.
| ||
Cell Prolif ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression | ||
Mol Oncol TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status. | ||
Cell Death Dis TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer. |
