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TRPA1 Polyclonal antibody, PBS Only

TRPA1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 19124-1-PBS

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Synonyms

验证数据展示

  • WB analysis using 19124-1-AP (same clone as 19124-1-PBS)

    WB analysis using 19124-1-AP (same clone as 19124-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 19124-1-AP (TRPA1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19124-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse cerebellum using 19124-1-AP (same clone as 19124-1-PBS)

    IHC staining of mouse cerebellum using 19124-1-AP (same clone as 19124-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 19124-1-AP (TRPA1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19124-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse cerebellum using 19124-1-AP (same clone as 19124-1-PBS)

    IHC staining of mouse cerebellum using 19124-1-AP (same clone as 19124-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 19124-1-AP (TRPA1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19124-1-PBS in a different storage buffer formulation.

产品信息

19124-1-PBS targets TRPA1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name transient receptor potential cation channel, subfamily A, member 1
Synonyms
Calculated Molecular Weight 140 kDa
Observed Molecular Weight 120-130 kDa
GenBank Accession NumberNM_007332
Gene Symbol TRPA1
Gene ID (NCBI) 8989
RRIDAB_10642143
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO75762
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TRPA1, also named as ANKTM1, belongs to the transient receptor family. TRPA1 is a receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function. TRPA1 has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes. It acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana. It may be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds.