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TRPA1-IN-2

TRPA1-IN-2 是一种有效且具有口服活性的 TRPA1 抑制剂，IC50 值为 0.04 µM。TRPA1-IN-2 具有抗炎活性。

CAS号

2415206-22-1

分子式

C24H25F3N4O

主要靶点

TRP/TRPV Channel

仅限科研使用

Cat No : CM18993

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Synonyms

验证数据展示

  • CAS No.: 2415206-22-1

    TRPA1-IN-2
    CAS#: 2415206-22-1

产品信息

TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.

CAS号 2415206-22-1
分子式 C24H25F3N4O
主要靶点 TRP/TRPV Channel
主要通路 离子通道
分子量 442.48
纯度 98.05%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件
别名

靶点活性

TRPA1:0.04 μM

体内活性

TRPA1-IN-2 (90 mg/kg; i.p. in mice; 30 mg/kg i.p. in rats; 100 mg/kg; orally) reduced the total number of white blood cells and eosinophils in BALF. It has anti-inflammatory activity.[1]

参考文献

1.YunFeng Cheng, et al. Heteroaromatic acetamide derivative, and preparation and use thereof. WO2020244460A1.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2