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TRPV1 Monoclonal antibody, PBS Only

TRPV1 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1A3C9

Cat no : 66983-1-PBS

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Synonyms

Capsaicin receptor, DKFZp434K0220, Osm 9 like TRP channel 1, OTRPC1, TRPV1, Vanilloid receptor 1, VR1

验证数据展示

  • WB analysis of HepG2 using 66983-1-Ig (same clone as 66983-1-PBS)

    WB analysis of HepG2 using 66983-1-Ig (same clone as 66983-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 66983-1-Ig (TRPV1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66983-1-PBS in a different storage buffer formulation.

产品信息

66983-1-PBS targets TRPV1 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen TRPV1 fusion protein Ag18683 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name transient receptor potential cation channel, subfamily V, member 1
Synonyms Capsaicin receptor, DKFZp434K0220, Osm 9 like TRP channel 1, OTRPC1, TRPV1, Vanilloid receptor 1, VR1
Calculated Molecular Weight 839 aa, 95 kDa
Observed Molecular Weight 105 kDa
GenBank Accession NumberBC132820
Gene Symbol TRPV1
Gene ID (NCBI) 7442
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8NER1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TRPV1, also named as VR1 or OTRPC1, belongs to the transient receptor potential (TRP) family and TRPV subfamily (PMID: 17579562). TRPV1 is a ligand-activated non-selective calcium permeant cation channel expressed predominantly by sensory neurons (PMID: 10821274). It is involved in detection of noxious chemical and thermal stimuli. TRPV1 plays an important role in inflammatory thermal hyperalgesia (PMID: 10764638; 10821274).