验证数据展示
经过测试的应用
| Positive WB detected in | mouse colon tissue, rat colon tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 2 publications below |
产品信息
12293-1-AP targets TSPAN6 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human, rat |
| 免疫原 | TSPAN6 fusion protein Ag2964 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | tetraspanin 6 |
| 别名 | A15 homolog, T245, T245 protein, tetraspanin 6, Tetraspanin TM4 D, TM4SF6, TSPAN 6, TSPAN6 |
| 计算分子量 | 245 aa, 28 kDa |
| 观测分子量 | 25-30 kDa |
| GenBank蛋白编号 | BC012389 |
| 基因名称 | TSPAN6 |
| Gene ID (NCBI) | 7105 |
| RRID | AB_2213446 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O43657 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
TSPAN6 (also known as TM4SF6) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN6 gene is widely expressed, with high mRNA levels in liver, pancreas, kidney, and ovary (PMID: 9782095). TSPAN6 has been reported as a negative regulator of the RLR pathway by interacting with MAVS in a ubiquitination-dependent manner (PMID: 22908223).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for TSPAN6 antibody 12293-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Stem Cell Res Ther Research on the TSPAN6 regulating the secretion of ADSCs-Exos through syntenin-1 and promoting wound healing | ||
Eur J Med Res Diagnostic and prognostic significance of tetraspanin 6 and its role in facilitating glioma progression |
