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Species Reactivity
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验证数据展示

  • WB analysis using 14081-1-AP

    WB analysis using 14081-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 14081-1-AP (TSSK6 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours.

TSSK6 Polyclonal antibody

TSSK6 Polyclonal Antibody for WB, ELISA
Cat No. 14081-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, ELISA

别名

SSTK, Small serine/threonine kinase, Serine/threonine-protein kinase SSTK, EC:2.7.11.1, CT72

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inmouse testis tissue, rat testis tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:2000-1:12000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

14081-1-AP targets TSSK6 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 TSSK6 fusion protein Ag5209 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 testis-specific serine kinase 6
别名 SSTK, Small serine/threonine kinase, Serine/threonine-protein kinase SSTK, EC:2.7.11.1, CT72
计算分子量30.3 kDa
观测分子量30 kDa
GenBank蛋白编号BC014611
基因名称 TSSK6
Gene ID (NCBI) 83983
RRIDAB_3669176
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BXA6
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

TSSK6 (testis-specific serine kinase 6) is a testis-specific protein kinase that is highly conserved in mammals and essential for spermatogenesis. In spermatozoa, TSSK6 is expressed after meiosis and is localized to the nucleus of spermatocytes and to the posterior part of the head of spermatocytes. TSSK6-deficient spermatozoa exhibit a defective histone-to-fischerin transition (required for chromatin remodeling after meiosis), as well as a reduction in actin polymerization in spermatocytes. The result is striking morphological defects in the spermatozoa, including nuclear malformations, a hairpin shape with the head facing backward, or complete separation of the head. In addition, Tssk6 is frequently aberrantly expressed in colorectal cancer and exhibits oncogenic activity.

实验方案

Product Specific Protocols
WB protocol for TSSK6 antibody 14081-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols