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验证数据展示

  • WB analysis of NIH/3T3 using 11752-1-AP (same clone as 11752-1-PBS)

    WB analysis of NIH/3T3 using 11752-1-AP (same clone as 11752-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 11752-1-AP (TWIST2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11752-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

TWIST2 Polyclonal antibody, PBS Only

TWIST2 Polyclonal Antibody for WB, Indirect ELISA
Cat No. 11752-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy TWIST2 Ready-To-Use IHC Kit. TWIST2 primary antibody included.

产品信息

11752-1-PBS targets TWIST2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 TWIST2 fusion protein Ag2348 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 twist homolog 2 (Drosophila)
别名
计算分子量 160 aa, 18 kDa
观测分子量 21 kDa, 60 kDa
GenBank蛋白编号BC033168
基因名称 TWIST2
Gene ID (NCBI) 117581
RRIDAB_2877791
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ8WVJ9
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TWIST2, also named as BHLHA39 and DERMO1,is a basic helix-loop-helix protein which acts as a transcriptional regulator, plays a central role in differentiation of mesodermal during embryogenesis. TWIST2 inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors. It is also implicated in tumorigenesis, invasion and metastasis. TWIST2 forms both homodimers(45KD) and heterodimers with E2A E proteins, and dimer partner selection is a critical mediator of TWIST function. (PMID:14724576, 16502419).