验证数据展示
产品信息
11203-1-PBS targets TXNL6 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | TXNL6 fusion protein Ag1691 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | nucleoredoxin-like 1 |
别名 | |
计算分子量 | 24 kDa |
观测分子量 | 26-28 kDa |
GenBank蛋白编号 | BC014127 |
基因名称 | NXNL1 |
Gene ID (NCBI) | 115861 |
RRID | AB_2158126 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q96CM4 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
TXNL6, also named as NXNL1, belongs to the nucleoredoxin family. It may play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods. TXNL6 is a Novel Oxidative Stress-Induced Reducing System for Methionine Sulfoxide Reductase A Repair of a-Crystallin and Cytochrome C in the Eye Lens. It serve as a reducing system for MsrA repair of the essential lens chaperone a-crystallin/sHSP and mitochondrial cytochrome c. TXNL6 is induced at high levels in human lens epithelial cells exposed to H2O2-induced oxidative stress.(PMID:21079812)