• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Thyroglobulin Monoclonal antibody, PBS Only

Thyroglobulin Monoclonal Antibody for IHC, IF-P, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

IHC, IF-P, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

4D3C5

Cat no : 60272-1-PBS

Print datasheet

Synonyms

TG, 4D3C5

验证数据展示

  • IHC staining of human thyroid using 60272-1-Ig (same clone as 60272-1-PBS)

    IHC staining of human thyroid using 60272-1-Ig (same clone as 60272-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human thyroid tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

  • IHC staining of human thyroid using 60272-1-Ig (same clone as 60272-1-PBS)

    IHC staining of human thyroid using 60272-1-Ig (same clone as 60272-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human thyroid tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

  • IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

    IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human thyroid cancer tissue using Thyroglobulin antibody (60272-1-Ig, Clone: 4D3C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

  • IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

    IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed human thyroid cancer tissue using Thyroglobulin antibody (60272-1-Ig, Clone: 4D3C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

  • IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

    IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human thyroid cancer tissue using Thyroglobulin antibody (60272-1-Ig, Clone: 4D3C5 ) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

产品信息

60272-1-PBS targets Thyroglobulin in IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications IHC, IF-P, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Thyroglobulin fusion protein Ag18070 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name thyroglobulin
Synonyms TG, 4D3C5
Calculated Molecular Weight 2768 aa, 305 kDa
GenBank Accession NumberBC140933
Gene Symbol Thyroglobulin
Gene ID (NCBI) 7038
RRIDAB_2881392
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP01266
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.