- Featured Product
- KD/KO Validated
Thyroid Hormone Receptor beta Polyclonal antibody
Thyroid Hormone Receptor beta Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Mouse and More (2)
Applications
WB, ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | mouse retina tissue, mouse eye tissue |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
21007-1-AP targets Thyroid Hormone Receptor beta in WB, IF, ELISA applications and shows reactivity with Mouse samples.
| Tested Applications | WB, ELISA Application Description |
| Cited Applications | WB, IF |
| Tested Reactivity | Mouse |
| Cited Reactivity | human, mouse |
| Immunogen | Thyroid Hormone Receptor beta fusion protein Ag15210 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) |
| Synonyms | c erbA 2, c erbA beta, ERBA BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB, THRB1, THRB2, Thyroid Hormone Receptor beta |
| Calculated Molecular Weight | 476 aa, 54 kDa |
| Observed Molecular Weight | 50 kDa |
| GenBank Accession Number | BC106929 |
| Gene Symbol | Thyroid Hormone Receptor beta |
| Gene ID (NCBI) | 7068 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P10828 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Thyroid hormone receptor beta (THRB), also known as ERBA2, NR1A2, and THR1, belongs to the nuclear hormone receptor family and NR1 subfamily. THRB is a nuclear hormone receptor that can act as a repressor or activator of transcription. Moreover, THRB is also a high-affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. THRB is the most abundant THR isoform in the liver but is also expressed in other tissues and mediates the effects of THs on hepatic carbohydrate and lipid metabolism (PMID: 34884910).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for Thyroid Hormone Receptor beta antibody 21007-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Theranostics Palmitoylation of PKCδ by ZDHHC5 in hypothalamic microglia presents as a therapeutic target for fatty liver disease
|