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Tiazofurin

Tiazofurin (NSC-286193) 是一种合成的核苷类似物，显示出抗肿瘤活性。 它在细胞内合成为 tiazole-4-carboxamide adenine dinucleotide (TAD)，TAD 可有效抑制 IMP 脱氢酶。

CAS号

60084-10-8

分子式

C9H12N2O5S

主要靶点

Dehydrogenase

仅限科研使用

Cat No : CM02959

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Synonyms

NSC 286193|Riboxamide|噻唑呋林

验证数据展示

  • CAS No.: 60084-10-8

    Tiazofurin
    CAS#: 60084-10-8

产品信息

Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent IMP dehydrogenase (IMPDH) inhibitor.

CAS号 60084-10-8
分子式 C9H12N2O5S
主要靶点 Dehydrogenase
主要通路 代谢
分子量 260.27
纯度 ， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 NSC 286193|Riboxamide|噻唑呋林

溶解度

DMSO:50 mg/mL (192.11 mM)

参考文献

1.Tricot G, Jayaram HN, Weber G, Hoffman R. Tiazofurin: biological effects and clinical uses. Int J Cell Cloning. 1990;8(3):161-170.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2