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验证数据展示

  • WB analysis using 31130-1-AP

    WB analysis using 31130-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31130-1-AP (Transthyretin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Transthyretin Polyclonal antibody

Transthyretin Polyclonal Antibody for WB, ELISA
Cat No. 31130-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive WB detected inhuman heart tissue, human plasma tissue, mouse brain tissue, mouse liver tissue, rat plasma tissue
Planning an IHC experiment? We recommend our IHCeasy TTR Ready-To-Use IHC Kit. TTR primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

31130-1-AP targets Transthyretin in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 transthyretin
别名
计算分子量16 kDa
观测分子量15 kDa
GenBank蛋白编号NM_000371.4
基因名称 TTR
Gene ID (NCBI) 7276
RRIDAB_3669866
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP02766
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol, through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver, choroid plexus, retinal pigment epithelium, and pancreas.Within the CNS, TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis). Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR),hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1). In addition, positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. However Western blot analysis using specific rabbit anti-mouse TTR reveals that TTR is absent from the cortex, hippocampus, and cerebellum and present in the choroid plexus. (PMID: 22103483, 16698124)

实验方案

Product Specific Protocols
WB protocol for Transthyretin antibody 31130-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols