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Triclabendazole sulfoxide

Triclabendazole sulfoxide (TCBZ-SO) 是 Triclabendazole 的主要血浆代谢产物。Triclabendazole sulfoxide 具有抗寄生虫活性。Triclabendazole sulfoxide 可以抑制膜转运蛋白ABCG2/BCRP 的活性。

CAS号

100648-13-3

分子式

C14H9Cl3N2O2S

主要靶点

BCRP|Parasite

仅限科研使用

Cat No : CM02961

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Synonyms

TCBZ-SO|三氯苯达唑亚砜

验证数据展示

  • CAS No.: 100648-13-3

    Triclabendazole sulfoxide
    CAS#: 100648-13-3

产品信息

Triclabendazole sulfoxide is a main plasma metabolite of Triclabendazole. Triclabendazole sulfoxide inhibits membrane transporter ABCG2/BCRP and exhibits anti-parasite effects.

CAS号 100648-13-3
分子式 C14H9Cl3N2O2S
主要靶点 BCRP|Parasite
主要通路 微生物学|离子通道
分子量 375.66
纯度 ， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 TCBZ-SO|三氯苯达唑亚砜

溶解度

DMSO:70 mg/mL (186.34 mM)

参考文献

1.Robinson MW, et, al. The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica. Parasitol Res. 2004 Feb;92(3):205-10. 2.Barrera B, et, al. The anthelmintic triclabendazole and its metabolites inhibit the membrane transporter ABCG2/BCRP. Antimicrob Agents Chemother. 2012 Jul;56(7):3535-43.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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