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Triheptanoin

Triheptanoin (IND 106011) 是合成的中链甘油三酯 (MCT)，由甘油主链上的三个奇数链 7-碳(庚酸)脂肪酸组成，可以用于研究遗传代谢紊乱。

CAS号

620-67-7

分子式

C24H44O6

主要靶点

Others

仅限科研使用

Cat No : CM11708

Print datasheet

Synonyms

IND106011|UX 007|三庚酸甘油脂|UX007|IND 106011|UX-007|IND-106011

验证数据展示

  • CAS No.: 620-67-7

    Triheptanoin
    CAS#: 620-67-7

产品信息

Triheptanoin is a fatty acid metabolic modulator. It potentially for the treatment of fatty acid oxidation disorders and GLUT1.

CAS号 620-67-7
分子式 C24H44O6
主要靶点 Others
主要通路 其他
分子量 428.61
纯度 98.00%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 IND106011|UX 007|三庚酸甘油脂|UX007|IND 106011|UX-007|IND-106011

溶解度

DMSO:50 mg/ml (116.66 mM)

参考文献

1.Vockley J, Marsden D, McCracken E, DeWard S, Barone A, Hsu K, Kakkis E. Long-term major clinical outcomes in patients with long chain fatty acid oxidation disorders before and after transition to triheptanoin treatment--A retrospective chart review. Mol Genet Metab. 2015 Sep-Oct;116(1-2):53-60. doi: 10.1016/j.ymgme.2015.06.006. Review. Erratum in: Mol Genet Metab. 2015 Nov;116(3):221. PubMed PMID: 26116311.
2.Vockley J, Charrow J, Ganesh J, Eswara M, Diaz GA, McCracken E, Conway R, Enns GM, Starr J, Wang R, Abdenur JE, Sanchez-de-Toledo J, Marsden DL. Triheptanoin treatment in patients with pediatric cardiomyopathy associated with long chain-fatty acid oxidation disorders. Mol Genet Metab. 2016 Nov;119(3):223-231. doi: 10.1016/j.ymgme.2016.08.008. PubMed PMID: 27590926.
3.Schwarzkopf TM, Koch K, Klein J. Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience. 2015 Aug 6;300:201-9. doi: 10.1016/j.neuroscience.2015.05.014. PubMed PMID: 25982559.
4.Nguyen TD, Shingu Y, Amorim PA, Schwarzer M, Doenst T. Triheptanoin Alleviates Ventricular Hypertrophy and Improves Myocardial Glucose Oxidation in Rats With Pressure Overload. J Card Fail. 2015 Nov;21(11):906-15. doi: 10.1016/j.cardfail.2015.07.009. PubMed PMID: 26209001.

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