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Urocortin Recombinant antibody, PBS Only

Urocortin Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241183B12

Cat no : 84380-1-PBS

Print datasheet

Synonyms

UCN, UROC, UI, 241183B12

验证数据展示

  • WB analysis using 84380-1-RR (same clone as 84380-1-PBS)

    WB analysis using 84380-1-RR (same clone as 84380-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84380-1-RR (UCN antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84380-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 84380-1-RR (same clone as 84380-1-PBS)

    IHC staining of mouse heart using 84380-1-RR (same clone as 84380-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 84380-1-RR (Urocortin antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84380-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 84380-1-RR (same clone as 84380-1-PBS)

    IHC staining of mouse heart using 84380-1-RR (same clone as 84380-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 84380-1-RR (Urocortin antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84380-1-PBS in a different storage buffer formulation.

产品信息

84380-1-PBS targets Urocortin in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name urocortin
Synonyms UCN, UROC, UI, 241183B12
Calculated Molecular Weight 13 kDa
Observed Molecular Weight22 kDa
GenBank Accession NumberNM_003353
Gene Symbol UCN
Gene ID (NCBI) 7349
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP55089
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Urocortin is a member of the sauvagine/corticotropin-releasing factor/urotensin I family that includes CRF, urotensin I, sauvagine, urocortin II and urocortin III. Urocortin is a potent anorexigenic peptide that induces fed-like motor activity when administered centrally or peripherally in fasted animals. Urocortin is also a potent and long-lasting hypotensive agent and increases coronary blood flow. Urocortin acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) and binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta. Urocortin is synthesized as precursor, which is subsequently processed to the mature biologically active peptide (a 40-amino acid Molecule ). The 22 kDa may be a urocortin 1 precursor protein (PMID: 28887029).