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UFP-101 acetate

UFP-101 acetate 是一种特异性和竞争性 NOP 受体拮抗剂 (pKi = 10.24)，其特异性是 δ、μ 和 κ 阿片受体的 3000 倍以上。

CAS号

TP2105L

分子式

C84H142N32O23

主要靶点

Opioid Receptor

仅限科研使用

Cat No : CM18708

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Synonyms

UFP-101 acetate(849024-68-6 free base)

验证数据展示

  • CAS No.: TP2105L

    UFP-101 acetate
    CAS#: TP2105L

产品信息

UFP-101 acetate is a selective and competitive antagonist of the NOP receptor (pKi = 10.24) with >3000-fold selectivity over δ, μ, and κ opioid receptors.

CAS号 TP2105L
分子式 C84H142N32O23
主要靶点 Opioid Receptor
主要通路 神经科学|内分泌与激素|G蛋白偶联受体
分子量 1968.23
纯度 95.92%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 UFP-101 acetate(849024-68-6 free base)

体内活性

In mice submitted to the forced swimming test, UFP-101 acetate elicits a pronounced acute and dose-dependent antidepressant-like effect[2].

溶解度

H2O:83.3 mg/mL (42.3 mM)

参考文献

1.Gavioli EC, et al. Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test. Eur J Neurosci. 2003;17(9):1987-1990.
2.Calo G, et al. [Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor. Br J Pharmacol. 2002;136(2):303-311.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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