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UGT3A1 Polyclonal antibody

UGT3A1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 17268-1-AP

Print datasheet

Synonyms

UDPGT 3A1, UDP-glucuronosyltransferase 3A1, EC:2.4.1.17

验证数据展示

  • WB analysis using 17268-1-AP

    WB analysis using 17268-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 17268-1-AP (UGT3A1 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inmouse colon tissue, mouse kidney tissue, rat colon tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:12000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

17268-1-AP targets UGT3A1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen UGT3A1 fusion protein Ag11020 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name UDP glycosyltransferase 3 family, polypeptide A1
Synonyms UDPGT 3A1, UDP-glucuronosyltransferase 3A1, EC:2.4.1.17
Calculated Molecular Weight 59 kDa
GenBank Accession NumberBC035012
Gene Symbol UGT3A1
Gene ID (NCBI) 133688
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6NUS8
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

UGT3A1 (UDP Glycosyltransferase Family 3 Member A1) belongs to UDP-Glucuronosyltransferases (UGTs) superfamily. UGTs are membrane-bound enzymes localized at the subcellular level in the endoplasmic reticulum (ER) with an active site facing the lumenal side of the ER membrane. The genetic variation in UGT enzymes can modulate its regulation and expression, influencing UGT activity and resulting in pharmacological and physiologic effects. UGT3 family enzymes (UGT3A1 and UGT3A2) are expressed in the thymus, testis, and kidney, with a potential role in the metabolism of ursodeoxycholic acid during the treatment of cholestasis or gallstones.

实验方案

Product Specific Protocols
WB protocol for UGT3A1 antibody 17268-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols