UNC5D-Specific Polyclonal antibody

UNC5D-Specific Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 20241-1-AP

Print datasheet

Synonyms

KIAA1777, Netrin receptor UNC5D, PRO34692, Protein unc 5 homolog 4, Protein unc 5 homolog D, unc 5 homolog D (C. elegans), UNC5D, Unc5h4



经过测试的应用

Positive WB detected inmouse kidney tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

20241-1-AP targets UNC5D-Specific in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse
Cited Reactivityhuman
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name unc-5 homolog D (C. elegans)
Synonyms KIAA1777, Netrin receptor UNC5D, PRO34692, Protein unc 5 homolog 4, Protein unc 5 homolog D, unc 5 homolog D (C. elegans), UNC5D, Unc5h4
Calculated Molecular Weight 106 kDa
Observed Molecular Weight 59-65 kDa
GenBank Accession NumberNM_080872
Gene Symbol UNC5D
Gene ID (NCBI) 137970
RRIDAB_10699878
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6UXZ4
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5D.

实验方案

Product Specific Protocols
WB protocol for UNC5D-Specific antibody 20241-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
human

Sci Adv

The FLRT3-UNC5B checkpoint pathway inhibits T cell-based cancer immunotherapies

Authors - Kushal Prajapati