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Species Reactivity
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Conjugate
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Conjugate
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UPK1B Polyclonal antibody, PBS Only

UPK1B Polyclonal Antibody for IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 26853-1-PBS

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Synonyms

验证数据展示

  • IHC staining of human urothelial carcinoma using 26853-1-AP (same clone as 26853-1-PBS)

    IHC staining of human urothelial carcinoma using 26853-1-AP (same clone as 26853-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 26853-1-AP (UPK1B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26853-1-PBS in a different storage buffer formulation.

  • IHC staining of human urothelial carcinoma using 26853-1-AP (same clone as 26853-1-PBS)

    IHC staining of human urothelial carcinoma using 26853-1-AP (same clone as 26853-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human urothelial carcinoma tissue slide using 26853-1-AP (UPK1B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26853-1-PBS in a different storage buffer formulation.

产品信息

26853-1-PBS targets UPK1B in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen UPK1B fusion protein Ag25471 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name uroplakin 1B
Synonyms
GenBank Accession NumberBC063568
Gene Symbol UPK1B
Gene ID (NCBI) 7348
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO75841
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-1B (UPK1B) belongs to the tetraspanin (TM4SF) family. UPK1B can promote the proliferation, invasion and metastasis of tumor cells and regulate the development and progression of tumors (PMID: 30229818).