USP44 Polyclonal antibody
USP44 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | human placenta tissue, mouse testis tissue |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
15521-1-AP targets USP44 in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | WB, ELISA Application Description |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human |
| Immunogen | USP44 fusion protein Ag7888 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | ubiquitin specific peptidase 44 |
| Synonyms | Deubiquitinating enzyme 44, Ubiquitin thiolesterase 44, USP44 |
| Calculated Molecular Weight | 81 kDa |
| Observed Molecular Weight | 81 kDa |
| GenBank Accession Number | BC030704 |
| Gene Symbol | USP44 |
| Gene ID (NCBI) | 84101 |
| RRID | AB_2213688 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9H0E7 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
USP44(Ubiquitin carboxyl-terminal hydrolase 44) belongs to a large family of cysteine proteases that function as deubiquitinating enzymes. It has a ZnF-UBP (zinc-finger ubiquitin-specific protease) domain and conserved cysteine, histidine and asparagine/aspartic acid residues characteristic of deubiquitinating enzymes. And USP44 can cleave ubiquitin from ubiquitinated substrates both in vitro and in vivo. The expression of endogenous mouse or human USP44 is very low. A localization study of USP44 showed its predominant expression in the nucleus(PMID:20402667).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for USP44 antibody 15521-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
J Clin Invest USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis. | ||
Nucleic Acids Res USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair. |
