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VAV1 Polyclonal antibody, PBS Only

VAV1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 16364-1-PBS

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Synonyms

VAV, Proto-oncogene vav, Proto oncogene vav



产品信息

16364-1-PBS targets VAV1 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, IP, Indirect ELISA Application Description
Tested Reactivity human
Immunogen VAV1 fusion protein Ag9049 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name vav 1 guanine nucleotide exchange factor
Synonyms VAV, Proto-oncogene vav, Proto oncogene vav
Calculated Molecular Weight 845 aa, 98 kDa
Observed Molecular Weight 98 kDa
GenBank Accession NumberBC013361
Gene Symbol VAV1
Gene ID (NCBI) 7409
RRIDAB_2213571
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP15498
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Vav proteins mainly act as enzymes that catalyze the activation step of Rho subfamily GTPases during cell signaling. There are three family members:VAV1, VAV2 and VAV3. Vav1 is specifically expressed in the hematopoietic system, whereas Vav2 and Vav3 are more ubiquitously expressed (PMID:14607270). Vav1 is physiologically active as a GDP/GTP nucleotide exchange factor (GEF) in the hematopoietic system (PMID:31654719).