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Anti-Mouse VCAM-1/CD106 Rabbit Recombinant Antibody, PBS Only

VCAM-1/CD106 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

240597C2

Cat no : 98059-1-PBS

Print datasheet

Synonyms

CD106, VCAM-1, Vcam1, Vcam 1, 240597C2

验证数据展示

  • FC experiment of mouse bone marrow cells using 98059-1-RR (same clone as 98059-1-PBS)

    FC experiment of mouse bone marrow cells using 98059-1-RR (same clone as 98059-1-PBS)

    1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse VCAM-1/CD106 Rabbit Recombinant Antibody (98059-1-RR, Clone:240597C2) or 0.25 ug Isotype Control and PE-conjugated Goat Anti-Rabbit IgG. Cell were then stained with APC Anti-Mouse CD11b. Cells were not fixed. This data was developed using the same antibody clone with 98059-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98059-1-RR

    Affinity and Kinetic Characterization of 98059-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98059-1-RR against Mouse VCAM-1/CD106 were performed. The affinity constant is below 1 pM.

产品信息

98059-1-PBS targets VCAM-1/CD106 in FC applications and shows reactivity with mouse samples.

Tested Applications FC Application Description
Tested Reactivity mouse
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name vascular cell adhesion molecule 1
Synonyms CD106, VCAM-1, Vcam1, Vcam 1, 240597C2
Calculated Molecular Weight81 kDa
GenBank Accession NumberCAA47989.1
Gene Symbol VCAM-1
Gene ID (NCBI) 22329
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP29533
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Vascular cell adhesion molecule 1 (VCAM1), also known as CD106, is a 110-kDa transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. VCAM1 is expressed by cytokine-activated endothelium, interacts with integrin VLA4 (α4β1) present on the surface of leukocytes, and mediates both adhesion and signal transduction. It is also expressed either constitutively or inducibly in a variety of other cell types, including vascular smooth muscle cells, differentiating skeletal muscle cells, renal and neural epithelial cells, macrophages (Kupffer cells), dendritic cells, and bone marrow stromal cells (PMID: 7507076, 11359843).